FABON Pharma

Wet Co Mill

250,000.00

Enhance your pharmaceutical manufacturing with our efficient Wet Co-Mills, designed for wet milling and mixing of powders and liquids to achieve fine particle size reduction and uniform dispersion. Ideal for wet granulation, slurry preparation, and formulation processes, these machines combine grinding and mixing in a single step to improve product consistency and process efficiency.

Constructed from GMP-grade stainless steel, our Wet Co-Mills feature adjustable milling speeds, easy cleaning, and robust construction to handle a wide range of materials while minimizing contamination risks. Suitable for both R&D and production scales, they ensure reliable performance and compliance with pharmaceutical standards.

Optimize your wet processing with our versatile and easy-to-operate Wet Co-Mills.

Wet Co Mill – Technical Specification & Use in Pharma & Food Industry

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A Wet Co Mill (Cone Mill) is used in the pharmaceutical and food industries for wet granulation, size reduction, and dispersion of particles in liquid or semi-solid formulations. It ensures uniform particle size distribution, improved solubility, and better mixing of active ingredients.

Technical Specifications of Wet Co Mill

  1. Construction Material

Stainless Steel (SS 316L for contact parts, SS 304 for non-contact parts) – ensures GMP & FDA compliance.

Electropolished Interior & Exterior – prevents contamination and allows easy cleaning.

Food-Grade Seals & Gaskets (Silicone/PTFE/EPDM) – ensures airtight sealing and prevents leaks.

  1. Milling & Processing Capacity

Capacity: 10 kg/hr to 5000 kg/hr, based on model and application.

Screen Sizes: Various mesh sizes available (typically 100 – 500 microns).

Blades & Rotor Design: Multiple blade options (impellers, knife-edge, etc.) for different material properties.

  1. Operating Speed & Control

Rotor Speed: 1000 – 3000 RPM, adjustable via Variable Frequency Drive (VFD).

Shear Force Control: Allows precise particle size reduction without excessive heat generation.

  1. Material Feeding & Discharge System

Hopper Feed System: Can be integrated with vacuum loading for contamination-free operation.

Pneumatic or Gravity Discharge: Ensures efficient material flow.

Closed-Loop System: Prevents dust and material loss during processing.

  1. Wet Milling Efficiency

Uniform Particle Size Distribution: Reduces particle size with minimal heat generation.

Homogeneous Mixing: Improves wet granule consistency before drying in Fluid Bed Dryer (FBD).

High Shear Milling: Enhances API solubility and bioavailability in pharmaceutical formulations.

  1. Cleaning & Safety Features

CIP (Clean-In-Place) System (Optional): Allows quick and efficient cleaning between batches.

Explosion-Proof Design (Optional): Available for solvent-based applications.

Safety Interlocks & Emergency Stop Button: Ensures operator safety.

  1. Power Requirement

Motor Power: 1 HP to 15 HP, based on capacity.

Power Supply: 220V/380V, 50/60Hz, available in different configurations.

8.Uses of Wet Co Mill in the Pharmaceutical Industry

    • Wet Granulation & Size Reduction
    • Used after Rapid Mixer Granulator (RMG) to achieve uniform wet granules before drying.
    • Preparation of Suspensions & Emulsions
    • Ensures homogeneous dispersion of active ingredients in liquid formulations.
    • Improved Bioavailability of API
    • Reduces particle size, enhancing dissolution and absorption of drugs.
    • Prepares Granules for Tablet & Capsule Manufacturing
    • Ensures consistent granule size, improving tablet compression.
    • Pre-Milling Before Fluid Bed Drying (FBD)
    • Wet milling prevents agglomeration and improves drying efficiency.

9.Uses of Wet Co Mill in the Food Industry

    • Food Powder Processing
    • Used for grinding wet food ingredients like spices, starches, and protein mixes.
    • Sauces & Liquid Blends
    • Ensures smooth, uniform consistency in ketchup, sauces, and purees.
    • Dairy & Nutritional Powder Processing
    • Enhances solubility and dispersion of milk powder, protein supplements, and infant formulas.
    • Wet Granulation of Food Ingredients
    • Used in nutraceuticals, dietary supplements, and health drinks production.
    • Beverage & Confectionery Industry
    • Used for mixing syrups, sugar solutions, and flavoring agents.

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FAQs

What is a Wet Co-Mill?
A Wet Co-Mill is a grinding and mixing machine used for wet milling, size reduction, and dispersion of wet granules, slurries, and pastes to achieve uniform particle size and consistency.
What industries use Wet Co-Mills?
Pharmaceutical manufacturing Food processing Chemical industry Cosmetics and personal care
How does a Wet Co-Mill work?
Wet material is fed between rotating and stationary grinding discs or blades that shear and crush the material. The combined action of grinding and mixing achieves size reduction and homogenous dispersion.
What are the main components of a Wet Co-Mill?
Grinding chamber with rotating discs/blades Feeding hopper Motor and gearbox assembly Discharge outlet Control panel (manual or automated) Water or solvent inlet (optional for cooling)
What materials can be processed?
Wet granules and slurries Pastes and semi-solids Viscous liquids
What are the advantages of a Wet Co-Mill?
Efficient size reduction and dispersion Uniform particle size distribution High throughput and productivity Easy operation and cleaning Adjustable grinding parameters for flexibility
What capacities are available?
Wet Co-Mills come in various sizes, typically from 10 liters to 500 liters or customized per process requirements.
Is the Wet Co-Mill cGMP compliant?
Yes, designed and manufactured to meet cGMP guidelines for sanitary operation and easy cleaning.
Can the Wet Co-Mill be automated?
Yes, automation options include PLC-based control for: Grinding speed adjustment Process timing Monitoring and alarms
How is the product discharged?
Discharge is typically via a bottom outlet valve or port, designed for easy emptying and minimal product loss.
What maintenance is required?
Routine cleaning and sanitization Inspection of grinding discs/blades for wear Lubrication of moving parts Checking motor and control systems
What safety features are included?
Emergency stop buttons Safety interlocks on access doors Overload protection on motors
Can the Wet Co-Mill be customized?
Yes, customizations can be made in: Capacity and size Materials of construction (SS 316L, etc.) Automation and control features Integration with upstream and downstream equipment
How do I select the right Wet Co-Mill?
Consider: Batch size and production volume Material viscosity and particle size goals Process flow and space constraints Desired level of automation Our technical team is available to help choose the best model for your needs.
What documentation is provided?
Design and engineering specifications Operation and maintenance manuals Validation protocols (DQ, IQ, OQ, PQ) Material test certificates
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