Solution Preparation Tank

Description

Solution Preparation Tank is a dedicated vessel utilized in the pharmaceutical sector to dissolve, blend, and homogenize different ingredients, producing a homogeneous solution for subsequent processing or packaging. These tanks play a critical role in the manufacture of liquid formulations, syrups, suspensions, and other medicinal solutions.

Technical Specifications:

Material of Construction:

Stainless Steel: Tanks are generally made of high-grade stainless steel (SS304 or SS316) to provide corrosion resistance, strength, and adherence to hygienic standards.

Fibre-Reinforced Plastic (FRP): FRP tanks are used in some applications because they are corrosion-proof and structurally strong.

Capacity:

Production requirements determine capacities, which range from laboratory tank minifactories of a few liters to industrial tanks with a volume of several thousand liters.

Design Features:

Agitation System: Fitted with agitators or mixers to provide complete mixing and dissolution of ingredients. High-shear mixers are utilized to produce emulsions, suspensions, and lyosols, providing uniform particle size reduction and dispersion.

Heating and Cooling Jackets: Jackets on some tanks provide temperature control during the mixing process, which is critical for temperature-sensitive formulations.

CIP/SIP Systems: Integrated Clean-In-Place (CIP) and Sterilization-In-Place (SIP) systems allow automated cleaning and sterilization, ensuring aseptic conditions.

Surface Finish:

Interior is polished to mirror finish (generally Ra ≤ 0.5 µm) to inhibit microbial growth and to enable easy cleaning.

Instrumentation:

Equipped with sensors and controls for monitoring temperature, pH, and mixing speed to ensure accurate process control.

Uses:

Solution Preparation:

Dissolving active pharmaceutical ingredients (APIs) and excipients to form homogeneous liquid formulations.

Buffer and Media Preparation:

Preparation of buffers and culture media for different pharmaceutical processes like fermentation and cell culture.

Cleaning Solutions:

Blending cleaning chemicals applied in CIP systems to keep equipment clean.

In conclusion, solution preparation tanks play a crucial role in pharmaceutical production, providing consistent quality and safety of liquid medicinal products