Clean in Place (CIP) and Wash in Place (WIP)

Description

Clean-in-Place (CIP) and Wash-in-Place (WIP) systems are an essential part of hygiene maintenance and avoiding cross-contamination in pharmaceutical production. Both systems automatically clean interior surfaces of equipment, pipelines, vessels, and connected fittings without disassembly. Both systems, however, clean equipment; CIP generally refers to a completely automated system, while WIP might be partially manual.

Technical Specifications:

Construction Materials:

Tanks and Piping: Made of high-grade stainless steel (AISI 316) to provide corrosion resistance and sanitary standards compliance.

Valves and Fittings: Constructed to be resistant to cleaning agents and high temperatures, providing durability and reliability.

System Components:

Cleaning Solution Tanks: Usually jacketed for temperature control, with capacities of approximately 250 liters, having conical bottoms for total drainage.

Heating Elements: Electric heaters built into tanks to attain and sustain the required cleaning solution temperatures.

Dosing Pumps: Peristaltic, piston, or membrane pumps to ensure accurate dosing of cleaning chemicals.

Centrifugal Pumps: For circulation of cleaning solutions in the system, promoting turbulent flow and efficient cleaning.

Control Systems: Computerized controls with programmable logic controllers (PLCs) to control cleaning cycles, check parameters, and provide repeatability.

Operational Parameters:

Flow Rates and Velocities: Specially designed to produce turbulent flow, which is generally at a rate of 1.5 meters per second, for efficient removal of residues.

JBTC

Temperature Control: Cleaning solutions are brought to the best temperatures for improved cleaning efficiency.

Chemical Concentration: Accurate management of cleaning agent concentrations to eliminate residue effectively without harming equipment.

Applications:

Equipment Cleaning: Cleaners are automated to clean reactors, mixers, blenders, tanks, and piping systems to eliminate product residues and impurities.

Process Efficiency: Decreases downtime incurred by manual cleaning, thus raising overall production efficiency.

Safety and Compliance: Guarantees standardized and verified cleaning procedures, adhering to regulatory requirements and preventing cross-contamination risks.

Installation of CIP and WIP systems in pharma manufacturing not only improves product quality and safety but also maximizes operational efficiency by minimizing labor and equipment downtime.