FABON Pharma

Solution Preparation Tank

150,000.00

Achieve precision and consistency in formulation with our high-performance Solution Preparation Tanks, engineered for the preparation, mixing, and storage of liquid solutions in pharmaceutical and biotech applications. These tanks are ideal for processes involving solvent preparation, buffer solutions, syrups, and active pharmaceutical ingredient (API) blending.

Solution Preparation Tank is a dedicated vessel utilized in the pharmaceutical sector to dissolve, blend, and homogenize different ingredients, producing a homogeneous solution for subsequent processing or packaging. These tanks play a critical role in the manufacture of liquid formulations, syrups, suspensions, and other medicinal solutions.

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Technical Specifications:

  1. Material of Construction:
    • Stainless Steel: Tanks are generally made of high-grade stainless steel (SS304 or SS316) to provide corrosion resistance, strength, and adherence to hygienic standards.
    • Fibre-Reinforced Plastic (FRP): FRP tanks are used in some applications because they are corrosion-proof and structurally strong.

2. Capacity:

Production requirements determine capacities, which range from laboratory tank minifactories of a few liters to industrial tanks with a volume of several thousand liters.

3. Design Features:

      • Agitation System: Fitted with agitators or mixers to provide complete mixing and dissolution of ingredients. High-shear mixers are utilized to produce emulsions, suspensions, and lyosols, providing uniform particle size reduction and dispersion.
      • Heating and Cooling Jackets: Jackets on some tanks provide temperature control during the mixing process, which is critical for temperature-sensitive formulations.
      • CIP/SIP Systems: Integrated Clean-In-Place (CIP) and Sterilization-In-Place (SIP) systems allow automated cleaning and sterilization, ensuring aseptic conditions.

4. Surface Finish:

Interior is polished to mirror finish (generally Ra ≤ 0.5 µm) to inhibit microbial growth and to enable easy cleaning.

5. Instrumentation:

Equipped with sensors and controls for monitoring temperature, pH, and mixing speed to ensure accurate process control.

6. Uses:

  • Solution Preparation: Dissolving active pharmaceutical ingredients (APIs) and excipients to form homogeneous liquid formulations.
  • Buffer and Media Preparation: Preparation of buffers and culture media for different pharmaceutical processes like fermentation and cell culture.
  • Cleaning Solutions: Blending cleaning chemicals applied in CIP systems to keep equipment clean.

In conclusion, solution preparation tanks play a crucial role in pharmaceutical production, providing consistent quality and safety of liquid medicinal products

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FAQs

What is a Solution Preparation Tank used for?
A Solution Preparation Tank is designed for mixing, dissolving, and preparing liquid solutions such as binders, adhesives, syrup bases, and other formulations in pharmaceutical and allied industries.
What are the key components of a Solution Preparation Tank?
Stainless steel tank (SS 304/316) with a jacket for heating/cooling (optional) Agitator (anchor, paddle, or propeller type) with motor and gearbox Inlet and outlet valves Manhole and sight glass for monitoring Temperature and level sensors (optional) Control panel for motor and temperature control
What materials are used in the construction?
Contact parts: SS 316 or SS 316L (corrosion-resistant and hygienic) Non-contact parts: SS 304 or mild steel with powder coating Surface finishes: Mirror or matt finish depending on hygiene requirements
Is the tank suitable for heating or cooling?
Yes, most tanks come with a jacket for indirect heating or cooling using steam, hot water, or chilled water, ensuring temperature control during solution preparation.
What sizes are available?
Standard tanks range from 50 liters to 2000 liters or customized as per batch size and process requirements.
Is the Solution Preparation Tank cGMP compliant?
Yes, the tank is designed following cGMP guidelines for pharmaceutical manufacturing, ensuring easy cleaning, no dead zones, and sanitary construction.
How is mixing achieved?
Mixing is done by an agitator driven by a motor, with options for variable speed control to optimize mixing efficiency for different viscosities and solution types.
Can the tank be automated?
Yes, automation options include: PLC/HMI control for agitator speed and temperature Level and temperature monitoring with alarms Recipe management and batch control
How is the solution discharged?
Solutions are discharged via bottom outlet valves (manual or pneumatic operated) or through a tilting mechanism (optional) for complete emptying.
What safety features are included?
Emergency stop on control panel Overload protection for motor Pressure relief valves (if jacket is pressurized) Interlocks for manhole and access points
What maintenance is required?
Regular cleaning after batches (CIP/SIP compatible options available) Inspection of seals, valves, and agitator components Lubrication of gearbox and motor as per schedule
Do you provide documentation and validation support?
Yes, we supply: DQ, IQ, OQ, PQ documentation Operation and Maintenance Manuals Calibration certificates and material test certificates
Can the tank be customized?
Yes. Customizations include: Capacity and dimensions Agitator type and speed Heating/cooling jackets Automation level Material of construction based on process needs
How do I select the right tank for my process?
Consider: Batch size and production volume Type of solutions (viscosity, chemical compatibility) Heating or cooling requirements Space constraints Automation preferences
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